With the fifth stage of Paris-Nice, from Cormoranche-sur-Saône to Colombier-le-Vieux, the peloton will face the longest stage, with 206.3 km and 2,735 meters of elevation gain and a maximum gradient of 13.3%. The race has entered its decisive phase with Vingegaard in the yellow jersey and the general classification taking on a more defined shape following the major chaos of yesterday's stage.

Today's stage will be characterized by three steep climbs in the final 35 kilometers, but the riders will encounter the first obstacle approximately 60 kilometers from the start when climbing towards Lentilly, covering 2.3 kilometers with an average gradient of 4.7%, before returning to flat terrain.

After covering approximately 100 kilometers, the peloton will encounter the Côte d'Échalas, with a length of 4.7 kilometers and an average gradient of 5.1%. After another 60 kilometers of easier riding heading towards the Rhône, the peloton will face the Côte de Sécheras, a 3.9-kilometer climb at 7%. At this point, less than 30 kilometers will remain to the finish and the most demanding part of the day will begin. The riders will now have to deal with the Côte de Saint-Jean-de-Muzols, stretching 2.2 kilometers with an average gradient of 11%, followed immediately by a descent. After this section, they will reach the Côte de Sainte-Barthélemy-le-Plain which will climb for 3.2 kilometers at 7.6%. The final kilometer will have a gradient of 2.9%.

Regarding time bonuses, the first three riders to cross the finish line will receive 10, 6, and 4 seconds of bonus time, while the intermediate sprint will award 6, 4, and 2 seconds.